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Jesus Araujo

Dr. Jesus Antonio Araujo, MD

Internal MedicineCardiovascular Disease

OVERVIEW

The main research interests of our laboratory are focused on two areas of investigation: 1) Environmental Cardiology: We are dissecting the mechanisms by which exposure to air particulate matter promotes atherosclerosis and ischemic heart disease and studying gene-environment interactions of relevance in the development of cardiovascular disease. We have determined that air pollutant chemicals such as those present in diesel exhaust particles are able to induce inflammatory genes in endothelial cells, in a synergistic fashion with oxidized phospholipids. This synergy was also present in tissues harvested from animals exposed to concentrated ambient ultrafine particles which are the smallest (<0.18 um) and most abundant particulate pollutants in urban settings, responsible for the largest promotion of atherosclerosis as compared with particles of bigger size. One of the mechanisms how air pollution appears to promote atherosclerosis is via the generation of dysfunctional HDL that either loses its anti-inflammatory capacity or even becomes proinflammatory. 2) Biology of vascular oxidative stress: We are interested in genes and pathways of relevance in the vascular oxidative stress generated in atherosclerosis and cardiac allograft rejection response, such as heme oxygenase-1 (HO-1) and its transcription factor Nrf2. We have shown that HO-1 is an important antioxidant and anti-inflammatory protective gene that may play a central role in orchestrating the antioxidant defense of vascular cells. We are currently studying how is that HO-1 expression modulates various inflammatory pathways via the use of genetic and biochemical approaches. We have established a good complementation in between our two areas of investigation as it appears that the generation of reactive oxygen species in the vasculature and the expression of Nrf2-regulated antioxidant genes represent important elements in the systemic effects of air particulate pollutants.
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PATIENT'S PERSPECTIVE

Takes time to answer my questions
Provides follow-up as needed

Based on patient feedback.

RATINGS AND REVIEWS

Dr. Araujo's Rating
5.0
Patient Perspective
n/a Explains conditions and treatments
5.0 Takes time to answer my questions
5.0 Provides follow-up as needed
Office Rating
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757 Westwood Plz, Los Angeles, CA, 90095
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Ronald Reagan University Of California Los Angeles Medical Center
757 Westwood Plz
Los Angeles, CA, 90095

LOCATIONS

200 Medical Plaza Steste 365c
Los Angeles, CA, 90095
Mon8:00 am - 5:00 pm
Tue8:00 am - 5:00 pm
Wed8:00 am - 5:00 pm
Thu8:00 am - 5:00 pm
Fri8:00 am - 5:00 pm
SatClosed
SunClosed

PROCEDURES PERFORMED

EDUCATION AND TRAINING

Medical School
Universidad Central De Venezuela Escuela De Medicina Luis Razetti
Graduated 1991
ALBANY MEDICAL COLLEGE
Residency
Ucla Medical Center

INSURANCE PLANS ACCEPTED  (47)

Please verify insurance information directly with your doctor's office as it may change frequently.
  • CIGNA PPO
  • CIGNA Open Access Plus
  • CIGNA HMO
  • Blue Cross CA PPO Prudent Buyer Large Group
  • BCBS Blue Card PPO
  • Blue Cross CA California Care Large Group HMO
  • Blue Shield CA PPO
  • Health Net CA HMO Employer Group
  • Health Net CA PPO
  • First Health PPO
  • UHC Choice Plus POS
  • UHC Options PPO
  • Blue Cross CA Select PPO
  • Blue Shield CA Access Plus HMO
  • Blue Cross CA PPO Prudent Buyer Individual
  • Blue Cross CA PPO Prudent Buyer Small Group
  • Blue Cross CA Select Plus HMO
  • Blue Shield CA Silver 70 PPO
  • BS CA Platinum 90 PPO
  • Blue Cross CA Advantage PPO Preferred DirectAccess Plus
  • Blue Shield CA Bronze 60 PPO SHOP
  • Blue Shield CA Bronze Full PPO 4500
  • Health Net CA Individual and Family PPO
  • Blue Shield CA Platinum Access+ HMO 25
  • Blue Cross CA Vivity
  • BC CA California Care Small Group HMO
  • Anthem Advantage HMO
  • Health Net CA HMO
  • MEDICA CHOICE WITH UNITEDHEALTHC
  • UHC Nexus Open Access
  • Blue Cross CA Anthem Advantage HMO
  • Blue Cross CA California Care Small Group HMO
  • Blue Shield CA Platinum 90 PPO
  • Blue Shield of CA 2021 I&F PPO Plan
  • LA Care
  • Medica Choice With UHC
  • Oscar Insurance CA
  • BCBS Pathway EPO
  • Oscar CA Cigna + Oscar Open Access Plus
  • Aetna Choice POS II
  • Aetna Managed Choice POS Open Access
  • Aetna Savings Plus of CA
  • Aetna HMO Deductible Plan CA only
  • Aetna Elect Choice EPO Open Access
  • Aetna Innovation Health Aetna Premier Care Network Plus
  • Aetna Open Choice PPO
  • Blue Cross CA Pathway EPO

HOSPITAL AFFILIATIONS

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