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Antonio Serna IV, M.D. can pinpoint the exact moment he knew he wanted to be a doctor, I was in high school and shadowed a physician for career day. We were helping people and I enjoyed the experience. That day, I knew that this is what I wanted to do. Dr. Serna then went on to pursue his dream, completing his Medical Doctorate at the University of Texas Southwestern School of Medicine, as well as his Fellowship in Gastroenterology at the University of New Mexico Health Science Center. After that, he chose the sub-specialty of gastroenterology due to the diversity of the field. He says, GI involves so many organs and organ systems. The work is interesting and diverse we problem solve and do procedures. When Dr. Serna is not practicing medicine, he is involved in the local community, such as dedicating time as a volunteer at camps for children suffering for Crohns and colitis. Dr. Serna has been heavily involved in campaigns in order to promote colon cancer awareness and prevention. In addition to these efforts, his involvement has even extended to features on local television programming. Dr. Sernas motivation comes from his patients. They are what makes practicing medicine so enjoyable. In his own words, The patients have to come first. When we put our patients first, we make a real difference, even when we cant offer a cure.
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Explains conditions and treatments
Takes time to answer my questions
Provides follow-up as needed
Office cleanliness

Based on patient feedback.


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Preferred Provider badge recognizes providers that are committed to transparency, responsiveness and great service to patients, and have earned a high patient satisfaction rating.


Dr. Serna's Rating
Patient Perspective
5.0 Explains conditions and treatments
4.5 Takes time to answer my questions
5.0 Provides follow-up as needed
Office Rating
Showing ratings for:
520 E Euclid Ave, San Antonio, TX, 78212
n/a Average office wait time
5.0 Office cleanliness
5.0 Courteous staff
5.0 Scheduling flexibility
San Antonio Gastroenterology
520 E Euclid Ave
San Antonio, TX, 78212
Showing 1-14 of 14 reviews
"Our visit was great! Very very good Dr. Serna. Explained everything and we were satisfied. "
  • June 5, 2024
"Very well acceptable, I feel very safe in his presence "
  • April 18, 2024
"Dr. Serna. A very good Doctor. Takes time to listen to you. Looks closely at your history. Explains well. Staff in the back are very kind and caring. The gals in the front…. One of them not so much. She always has an attitude with patients and guests. Very clean environment. OVERALL : 4 and One Half Stars"
  • April 11, 2024
"Very good doctor very kind and understanding well recommend him to anybody who is looking for a good doctor"
  • March 20, 2024
"I had not been seen by Dr. Serna in almost two years, yet he approached me with full knowledge & concern regarding my recurring gastric problems & ready to find solutions. Office & Nursing Staff is very welcoming & patient. Thank you."
  • February 19, 2024
"great like always Dr. Serna is great with my sister needs even thou she is nonverbal and handicapped he has helped us so much thank you Dr. and staff been with him since 2013??????"
  • January 12, 2024
"Dr. Serna and Staff are absolutely the best. "
  • December 3, 2023
"Dr. Serna provided the care that I needed in an unexpected timeframe. I am very appreciative of his professionalism and concern for my health. "
  • October 28, 2023
"Excellent service. The doctor and his work team make you feel confident and safe at all times."
  • October 13, 2023
"Dr. Serna is great and makes you feel at ease when explaining your results. "
  • September 29, 2023
"It was good. I love the service. "
  • September 11, 2023
"I love how Dr Serna takes his time with hus patients and is so thorough! Always smooth appointments with him"
  • September 11, 2023
"Dr.cerna is an excellent gastroenterologist and the staff has a very good attitude, I really recommend it"
  • September 6, 2023
"Dr . Serna is very professional and he know his work . He gave me a medication that is working a miracle on my ibs . "
  • October 3, 2022


San Antonio - Downtown
520 E Euclid Ave
San Antonio, TX, 78212
  • Accepting New Patients
  • Accepting New Patients
Mon6:00 am - 5:00 pm
Tue6:00 am - 5:00 pm
Wed6:00 am - 5:00 pm
Thu6:00 am - 5:00 pm
Fri6:00 am - 5:00 pm
Baptist Medical Center
111 Dallas St
San Antonio, TX, 78205
111 Dallas St
San Antonio, TX, 78205
1310 McCullough Ave
San Antonio, TX, 78212




Medical School
University of Texas Southwestern


Please verify insurance information directly with your doctor's office as it may change frequently.
  • BCBS Blue Card PPO
  • Humana National POS
  • BCBS TX BlueChoice
  • Aetna Choice POS II
  • Aetna HMO
  • Humana HMO
  • UHC Navigate POS
  • Humana Preferred PPO
  • First Health PPO
  • Humana HMO Premier
  • Oscar - San Antonio MRF
  • Aetna Signature Administrators PPO
  • UHC Choice Plus POS
  • Humana HMO Premier MRF
  • Humana National HMO
  • UHC Navigate HMO
  • Humana San Antonio HMOx
  • Humana Choice POS
  • Aetna Managed Choice POS Open Access
  • UHC Options PPO
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  • CIGNA Open Access Plus
  • BCBS TX Blue Advantage HMO
  • Multiplan PPO
  • Ambetter from Superior HealthPlan MRF
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  • BCBS TX HMO Blue Texas
  • Imagine Health Innovative Health
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  • Aexcel PPO
  • Blue Essentials HMO
  • Molina place TX
  • Oscar Insurance TX
  • TX Ambetter
  • UHC Nexus Open Access
  • Aetna Elect Choice EPO Open Access
  • Aetna Innovation Health Aetna Premier Care Network Plus
  • Aetna Open Choice PPO
  • Ambetter TX
  • AWH BaptistHealth HealthTexas Managed Choice
  • BCBS TX Blue Essentials HMO
  • Humana / ChoiceCare Network PPO
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  • Medica Choice With UHC
  • Molina Marketplace TX
  • Oscar EPO TX


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