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OVERVIEW

Akil Merchant, MD, is an NIH funded physician-scientist who focuses on developing new treatments for blood cancers such as leukemia and lymphoma. In particular, he studies how interactions between tumor cells, cancer stem cells and the tumor immune microenvironment can drive the progression of tumors and resistance to chemotherapies. The work in the lab is organized in two major themes: 1) Hedgehog signaling in normal and malignant hematopoiesis. Currently we have two projects in the lab focused on Hedgehog signaling. The first is focused on understanding how loss of Gli2 and Gli3 disrupts stem cell function in normal hematopoietic stem cells. The aim of the second project is to understand how mutant JAK/STAT (JAK2V617F) signaling interacts with Hh/Smo activity in myeloproliferative neoplasms to drive fibrosis in the bone marrow. 2) Multiplex Imaging of the Tumor Microenvironment (TME). Dr. Merchant is a leader in applying imaging mass cytometry (IMC) to the study of the tumor immune microenvironment and is the founding director of the IMC Shared Resources Core at Cedars-Sinai. IMC is a novel imaging technology that allows for the simultaneous measurement of over 40 proteins in a single slice of tissue, at single cell resolution. Ultimately our goal is better understand the immune response to cancer so we can predict which patients will respond to treatment with immuno-oncology drugs and identify new immuno-oncology targets in the future.
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PATIENT'S PERSPECTIVE

Explains conditions and treatments
Takes time to answer my questions
Provides follow-up as needed

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RATINGS AND REVIEWS

Dr. Merchant's Rating
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Patient Perspective
5.0 Explains conditions and treatments
5.0 Takes time to answer my questions
5.0 Provides follow-up as needed
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8700 Beverly Blvd, Los Angeles, CA, 90048
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8700 Beverly Blvd
Los Angeles, CA, 90048

LOCATIONS

8700 Beverly Blvd
Los Angeles,CA,90048
  • Accepting New Patients
  • Accepting New Patients
127 S San Vicente Blvd 7th Floor
Los Angeles,CALIFORNIA,90048
  • Accepting New Patients
Mon8:00 am - 5:30 pm
Tue8:00 am - 5:30 pm
Wed8:00 am - 5:30 pm
Thu8:00 am - 5:30 pm
Fri8:00 am - 5:30 pm
SatClosed
SunClosed
  • Accepting New Patients

CONDITIONS TREATED

  • Acute Myeloid Leukemia (aml)
  • Dermal Aesthetics
  • Extra Corporeal Shockwave Therapy
  • Leukemia
  • Lymphoma

SPECIALTIES

  • Hematology/oncology

EDUCATION AND TRAINING

Fellowship
Johns Hopkins University
Graduated 2010
Residency
Baylor College of Medicine
Graduated 2005
Medical School
Baylor College of Medicine
Graduated 2000

INSURANCE PLANS ACCEPTED

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